New type of cancer treatment

[Mikey da Murph]

Saw a movie last night called "Burzynski", it's a documentary about Dr. who has pioneered a new means treating cancer. Thsi clip from the beginning was especially moving for me:



A cop talks about his daughter who had cancer, the agony she went thru during radiation/ chemo, how Dr. Burzynski's treatment helped cure her, and how she died, cancer-free, b/c of damage sustained through conventional cancer treatments.

Here's a link to the whole movie:



And it's also available to watch instantly online via Netflix.

[Mikey da Murph]

This is from 1995

[eL FryEdo]

if its true why isnt this guy blowing up is my question

[TrippinFace101]

The only way to cure cancer is to catch it in time. Ask my relatives that didnt and they are no longer with us.

[Mikey da Murph]

Trippin, catching it early definitely is important... but once caught, what's the best treatment method? We've been using chemo/ radiation for many years... you'd think with all the money spent on cancer research, there'd be new treatment methods being discussed and explored all the time.

Freydo, I would say that the FDA suing this guy for years and years, and not having any official agencies declare it as effective or safe, is a big hurdle to it gaining popularity. however, he finally won his case, and with this movie (which won best documentary at soem film festival I forget the name of), perhaps the idea will begin to spread.

Here's a bit of history on the legal casea and outcomes: http://thenewamerican.com/reviews/mo...rious-business



The persecution started in the mid 1980s with the Texas Board of Medical Examiners, which attempted to revoke Dr. Burzynski’s license to practice medicine. They failed. But the years of state-level harassment, investigations, and court proceedings — which were eventually discovered to be the result of pressure from the FDA — were only the start of the doctor‘s problems with authorities.

Next came the open assault by the federal government. First the FDA filed a civil lawsuit against Dr. Burzynski trying to shut down his clinic and prevent his patients from receiving their medicine. The agency warned the judge that if the court would not grant the injunction it was seeking, the federal government would be forced to use “less efficient” methods to shut down Dr. Burzynski — methods like propaganda, raids, and even criminal prosecution.

After failing to squash Dr. Burzynski in civil court, the feds took their war to the next level. The first grand jury was convened in 1985 in an effort to get an indictment. As part of the new strategy, the FDA raided Dr. Burzynski’s clinic and seized all of his patients’ medical records. They failed to get an indictment.

The next year, prosecutors seized more “evidence.” Still no indictment. In 1990, yet another grand jury was convened. And once again, it refused to indict. Then another grand jury. No indictment. And then another. At no point did the FDA claim that antineoplastons were not safe or effective.

After failing to get an indictment with at least five grand juries, however, the federal government and the cancer industry were really getting frustrated. The FDA began issuing subpoenas to anyone and everyone associated with Dr. Burzynski: other doctors, patients, and even journalists who had written favorably about Dr. Burzynski and his work. Finally, in 1995, Congress stepped in.

“In my opinion, you have every right to use the investigative authority and the judicial resources of the federal government to the justice department convene a grand jury, that’s very appropriate, the first time, perhaps even the second time,” Rep. Joe Barton told the FDA Commissioner during a hearing of the House Oversight and Investigations Subcommittee shown in the documentary. “It becomes questionable the third time. The fourth time and the fifth time, it is not, I think, an illogical conclusion to think that the FDA has a vendetta against Dr. Burzynski, or wants to retaliate for some reason.”
FDA boss David Kessler appeared uncomfortable. But Rep. Barton kept piling it on: “How many grand jury investigations have to occur that result in no finding of fault before you as commissioner of the FDA would encourage those within your organization to cease and desist?” Kessler never did answer the question.

Then another Congressman at the hearing chimed in. After confirming that there had indeed been at least four unsuccessful attempts to get a grand-jury indictment, the committee member says: “I am left then, with rather strong inference, that if you convene four separate grand juries and there is no indictment returned — not withstanding that prosecutors tell us always that it’s possible to indict a ham sandwich — that probably there’s not much there.”

A lot of Dr. Burzynski’s patients testified at the hearing, too. “What the classical conventional medicine had to do for me was there — nothing,” noted an obviously distraught middle-aged man who had been treated with antineoplastons. “For me, the next thing was the minister. I did not want to undergo chemotherapy — which I had a new name for, ‘kill ‘em therapy’ — or any type of radiation.”

He also praised Dr. Burzynski and blasted the FDA. “I was extremely lucky that I found Dr. Burzynski. And I don’t want the FDA to take this right from me,” he said. “I came eighteen years ago from Communist Romania, and the tyrant dictator Ceauscescu never stopped a doctor from treating anybody. How can we have something like this in the United States?”

[TrippinFace101]

So hard to determine what works and what doesnt. But your days are numbered the day you are born have fun in between.

[James Maxx]

if its true why isnt this guy blowing up is my question

Because cancer is big business, and the FDA is in bed with the pharmacy companies so its in their best interest to put this guy in jail or make up some other lame legal excuse to prevent him from continuing his treatments.

Its a good documentary. This guy basically has the cure for cancer and he explains how he can cure brain tumors, which are the hardest to get rid of.

[Dancefloorhewa21]

The Isreali's came up with another new way some new needle you inject into the tumor and it dissolves it. 100% cured in every animal they tested it on after they put human cancer cells in them . Let me find the article you have to use google translate its in hebrew.

[StateOfTrance]

I saw an article on my iPad a few weeks ago about a revolutionary cancer vaccine. It is not a typical vaccine in that this you take after you have been diagnosed so it is a treatment, and what it does is it can somehow mark the cancer cells so that your own white blood cells can identify and kill them and leave your healthy cells alone. In theory and in testing that has been done this is effective for all types of cancers too. When I got on my desktop I did a google search on it and was able to find the home site of this company fairly quickly. I just tried to find that site again and I can't.

[Dancefloorhewa21]

Ok found it! Google translated it for you all...
Israeli researchers have found a cure for cancer?
An important discovery at Tel Aviv: Israeli researchers have developed two tiny needle she could suppress tumor growth and prevent the regeneration. In experiments carried out to date on the mouse succeed 20 different types of tumors
News 2 | 07:12:11 | 17:28
Photo: Is a cure for cancer found? Illustration | Reuters
Share
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Israeli development will find a cure for cancer? Tel Aviv University researchers have developed a small needle, she could cure cancer tumors in mice, and immunized against renewal of cancer.
Professor imperial pigeon and Prof. Yitzhak Klzon Faculty of Medicine at Tel Aviv University are developing the innovative needle, emits alpha particles directly into the tumors, according to the reporting network in. During the experiments conducted by the tiny needle was introduced into the tumor, and she released particles absorbed in the cells relating to - have undermined the stability and caused them to disintegrate.
Needle after use, researchers noticed that the action causes serious damage to tumor cells and leads to collapse, so no side effects. The experiments performed so far have been on mice, and recorded success in treating some 20 different types of tumors, including tumor cells of mice transplanted human beings.
The researchers emphasize that development is only in its first. Treatment published to date in several leading journals Cancer Research, and Tel Aviv University wrote him several patents and has established a commercial company which should lead to human clinical trials innovative therapy. His first experiments are expected to take place at Beilinson Hospital in Petah Tikva.

http://reshet.ynet.co.il//ch2/News/E...cle,84838.aspx

[joonbug1104]

you'd think with all the money spent on cancer research, there'd be new treatment methods being discussed and explored all the time.

There is constant research and development of new products (chemotherapy, biologics, etc) for cancer. Where are you getting your information from?

Perhaps the biggest issue with new treatments is patients not willing to "try" new agents. Most people choose the conventional treatments and are afraid to partake in any trials of new drugs until they are told they have 5 days to live then its too late for any drug to work. limited people willing to participate means limited research data, which in turn limits the ability of these drugs to get further researched and approved, therefore limiting the medications available to cancer patients. Even in Bridzinskis case.. there is probably little research or "legit" research.
Cancer is a terrible animal. Prevention and early detection are the only things we can do to prevent/limit its progress.

The first vaccine against a particular type of cancer was recently developed. Can anyone tell me which vaccine it is? :o)

and im not talking about the vaccine that someone posted a few posts up...

[joonbug1104]

So hard to determine what works and what doesnt. But your days are numbered the day you are born have fun in between.

well since your "trippinface" you're clearly having fun in between lol

[TrippinFace101]

well since your "trippinface" you're clearly having fun in between lol

No shit sherlock lol.

[joonbug1104]

i want my old username back!!!! someone send me my old passsword! :o)

[TrippinFace101]

i want my old username back!!!! someone send me my old passsword! :o)

Whats your old UN mark c lol

[eL FryEdo]

Because cancer is big business, and the FDA is in bed with the pharmacy companies so its in their best interest to put this guy in jail or make up some other lame legal excuse to prevent him from continuing his treatments.

Its a good documentary. This guy basically has the cure for cancer and he explains how he can cure brain tumors, which are the hardest to get rid of.

i 100% agree ... but with enough successful treatments i would think by now this would be big news across the country and the world

[StateOfTrance]

http://www.geek.com/articles/geek-ce...ticle-2011128/

17-year-old wins 100k for creating cancer-killing nanoparticle

At the age of 17 I was paying attention in college, but still enjoying the student life as much as studying towards my career goals. What I wasn’t doing was working at the cutting edge of cancer treatment and developing a potential cure.

Angela Zhang is, and she’s just been awarded the $100,000 Grand Prize in the Individual category of the Siemens Competition in Math, Science & Technology. Her project was entitled “Design of Image-guided, Photo-thermal Controlled Drug Releasing Multifunctional Nanosystem for the Treatment of Cancer Stem Cells.”

Her creation is being heralded as a “Swiss army knife of cancer treatment.” Zhang managed to develop a nanoparticle that can be delivered to the site of a tumor through the drug salinomycin. Once there it kills the cancer stem cells. However, Zhang went further and included both gold and iron-oxide components, which allow for non-invasive imaging of the site through MRI and Photoacoustics.

As to why she chose this as her project, Zhang explains that she was surprised when looking at the survival rates of patients receiving cancer treatment. As cancer stem cells are resistant to many forms of cancer treatment, it seemed like an area worth focusing on. Her nanoparticle is award-winning due to the fact it has the potential to overcome cancer resistance while offering up the ability to monitor the effects of the treatment in real-time using existing imaging techniques.

Zhang’s achievement is impressive considering she is only 17 years old, but also due to the level of understanding required to create such a nanoparticle in the first place. She has spent over 1,000 hours since 2009 researching and developing the particle, and wants to go on to study chemical engineering, biomedical engineering, or physics. Her dream job is to be a research professor.

The Siemens Competition is in its 13th year and aims to highlight talent at the high school level for those interested in science research. Last year 15-year-old Benjamin Clark won the Individual category for his work into how stars are born. In 2009 Ruoyi Jiang won for his research into chemotherapy drug resistance.

I think we can all agree this is a very worthwhile competition, and long may it continue if it pushes young minds to create solutions to some of our biggest problems.

[eL FryEdo]

^ thats awesome ... fucking geniuses

[SLAVE2THEMUZIK]

"Whats your old UN mark c lol"

no its SLAVE2THEMUZIK. before your time

[woo]

yeah the nano-particle approach is gaining ground for more precise delivery. pple get sick bc of what radiation does to the entire body... but delivering the hot dose closer to the actual diseased site is being rigorously researched.

http://chemistrynewsarticles.blogspo...ws+Articles%29


MONDAY, JANUARY 30, 2012

Nanoparticles refined for more accurate delivery of cancer drugs
A new class of nanoparticles, synthesized by a UC Davis research team to prevent premature drug release, holds promise for greater accuracy and effectiveness in delivering cancer drugs to tumors. The work is published in the current issue of Angewandte Chemie, a leading international chemistry journal.

In their paper, featured on the inside back cover of the journal, Kit Lam, professor and chair of the Department of Biochemistry and Molecular Medicine, and his team report on the synthesis of a novel class of micelles called dual-responsive boronate cross-linked micelles (BCMs) , which produce physicochemical changes in response to specific triggers.


A micelle is an aggregate of surfactant molecules dispersed in water-based liquid such as saline. Micelles are nano-sized, measuring about 25-50 nanometers (one nanometer is one billionth of a meter), and can function as nanocarriers for drug delivery.


BCMs are a unique type of micelle, which releases the payload quickly when triggered by the acidic micro-environment of the tumor or when exposed to an intravenously administered chemical compound such as mannitol, an FDA-approved sugar compound often used as a diuretic agent, which interferes with the cross-linked micelles.


"This use of reversibly cross-linked targeting micellar nanocarriers to deliver anti-cancer drugs helps prevent premature drug release during circulation and ensures delivery of high concentrations of drugs to the tumor site," said first author Yuanpei Li, a postdoctoral fellow in Lam's laboratory who created the novel nanoparticle with Lam. "It holds great promise for a significant improvement in cancer therapy."


Stimuli-responsive nanoparticles are gaining considerable attention in the field of drug delivery due to their ability to transform in response to specific triggers. Among these nanoparticles, stimuli-responsive cross-linked micelles (SCMs) represent a versatile nanocarrier system for tumor-targeting drug delivery.


Too often, nanoparticles release drugs prematurely and miss their target. SCMs can better retain the encapsulated drug and minimize its premature release while circulating in the blood pool. The introduction of environmentally sensitive cross-linkers makes these micelles responsive to the local environment of the tumor. In these instances, the payload drug is released primarily in the cancerous tissue.


The dual-responsive boronate cross-linked micelles that Lam's team has developed represent an even smarter second generation of SCMs able to respond to multiple stimuli as tools for accomplishing the multi-stage delivery of drugs to the complex in vivo tumor micro-environment. These BCMs deliver drugs based on the self-assembly of boronic acid-containing polymers and catechol-containing polymers, both of which make these micelles unusually sensitive to changes in the pH of the environment. The team has optimized the stability of the resulting boronate cross-linked micelles as well as their stimuli-response to acidic pH and mannitol.


This novel nano-carrier platform shows great promise for drug delivery that minimizes premature drug release and can release the drug on demand within the acidic tumor micro-environment or in the acidic cellular compartments when taken in by the target tumor cells. It also can be induced to release the drug through the intravenous administration of mannitol.


The study was funded by grants from the National Institutes of Health and a Department of Defense Breast Cancer Research Program Postdoctoral Award. Other authors are Wenwu Xiao, Kai Xiao, Lorenzo Berti, Harry P. Tseng, and Gabriel Fung of UC Davis; and Juntao Luo of SUNY Upstate Medical University, Syracuse, New York.


Story Source:



The above story is reprinted from materials provided by University of California - Davis Health System.


Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

Yuanpei Li, Wenwu Xiao, Kai Xiao, Lorenzo Berti, Juntao Luo, Harry P. Tseng, Gabriel Fung, Kit S. Lam. Well-Defined, Reversible Boronate Crosslinked Nanocarriers for Targeted Drug Delivery in Response to Acidic pH Values and cis-Diols. Angewandte Chemie International Edition, 2012; DOI: 10.1002/anie.201107144